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Reply.io

AI-powered multichannel sales outreach with autonomous SDR agents

Reply.io is an AI-driven sales engagement platform for B2B teams that automates outbound outreach across email, social, calls, and SMS. It can discover contacts, run conditional multichannel sequences, and use AI “SDR agents” to personalize messages, handle replies, and book meetings. Designed for sales teams and agencies that need scalable, high-deliverability outreach rather than manual one-off emailing.

Free Tier
Paid
Enterprise
Web
Chrome Extension
Integrations
B2B
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About

What It Is

Reply.io is a sales engagement and cold email platform that layers AI on top of traditional outbound workflows. It’s built for B2B sales teams and agencies that need to generate leads at scale, run structured outbound campaigns, and reliably turn website or list-based traffic into meetings.

The platform combines data sourcing, multichannel outreach, and meeting scheduling in one place. You can discover and enrich B2B contacts, push them into sequences spanning email, LinkedIn, SMS, calls, WhatsApp, and Zapier-connected channels, and let Reply’s AI SDR agents help with targeting, copy generation, and follow-up. It’s delivered as a web platform with a Chrome-based email search extension, and integrates with CRMs, Calendly, Gmail (via API), Google Postmaster, and other tools.

What to Know

Reply.io leans into agentic behavior more than many traditional sales engagement tools. The AI SDR component can propose audiences, generate outbound sequences across multiple channels, and automatically handle basic email replies and meeting booking once prospects respond. For teams focused on volume outbound, this can significantly reduce manual SDR workload while still keeping everything visible in a unified inbox and CRM-connected pipeline.

However, it’s still very much a sales-specific platform, not a general-purpose AI assistant. According to the site, it’s optimized for cold outreach, deliverability, and structured sequences, not for running complex custom business workflows outside sales. Details on the underlying AI models, data retention, and privacy policies aren’t provided on this page, so security-conscious or highly regulated organizations will need to review separate documentation. Pricing is partially clear (there is a Multichannel plan starting at $89 per user/month billed annually and a free, no-credit-card trial), but the full tier structure for Sales Outreach, AI SDR, and Agency plans isn’t fully readable here. Teams that don’t do outbound sales, or that only send a small number of highly personalized, manual emails, are unlikely to get full value from this tool.

Key Features
Audience discovery tools to build targeted B2B prospect lists
Access to over 1 billion global B2B contacts with real-time data and intent signals
AI SDR to suggest the right audience for campaigns
Chrome-based email search extension to find verified emails from LinkedIn and Gmail
One-click lead saving directly into your CRM
Use Cases
Automating outbound prospecting for a B2B SaaS sales team using AI to find contacts, run multichannel sequences, and book demos
Letting an AI SDR agent handle first-line replies to cold email campaigns, answer common questions, and schedule meetings for human reps
Running high-volume, multi-touch email and LinkedIn outreach for an agency managing outbound campaigns across many clients
Agenticness Score
11/ 20
Level 2: Capable

Handles multi-step tasks with guidance

Overall agenticness level: Level 2 (Score: 11/20).

Reply.io, particularly via its Jason AI SDR, is a capable, domain-specific agent for outbound sales. It can autonomously run multi-step, multichannel outreach campaigns, personalize and adapt messaging, handle replies, and book meetings while updating CRM and calendar systems. Its autonomy is strong within the sales engagement workflow but constrained to user-defined campaigns and goals. Adaptation and safety characteristics are present but not described in sufficient depth to score higher.

Dimension scores:

  • Action Capability: 3/4
  • Autonomy of Control Flow: 3/4
  • Adaptation and Recovery: 2/4
  • State and Continuity: 2/4
  • Safety and Observability: 1/4

Score Breakdown

Action Capability
3/4
Autonomy
3/4
Adaptation
2/4
State & Memory
2/4
Safety
1/4

Categories

Pricing
  • Free: No-credit-card signup with access to the platform; at least one 14-day trial is available for the Multichannel plan.
  • Pro ($89/mo): Multichannel plan starting from $89 per user/month billed annually, with all-inclusive outreach via email, LinkedIn, SMS, and phone at a fixed price.
  • Enterprise: Higher-volume Sales Outreach, AI SDR, and Agency plans with pricing based on active contacts and usage; contact sales for full details. Pricing for these tiers is not fully clear from the provided page content.
Details
Website: reply.io
Added: January 22, 2026
Last Verified: January 22, 2026
Agenticness: 11/20 (Level 2)
Cite This Listing
Name: Reply.io
URL: https://agentic-directory.onrender.com/t/replyio
Last Updated: January 29, 2026

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